Artificial sweeteners might make you lose your memory

While the jury is still out on whether diet and zero-sugar drinks are really better for your health than sugary sodas, a recent study has found that the artificial sweeteners they use may have one very unintended side effect: memory loss, particularly among younger consumers. But even though the study found a significant link between artificial sweeteners and memory issues, experts say this is still only a correlation, not causation.

What did the study find?

Several widely used artificial sweeteners may be “associated with faster declines in memory and thinking skills over time,” according to the study published by the American Academy of Neurology. It followed 12,772 adults in Brazil for about eight years and examined their intake of seven sugar substitutes: aspartame, saccharin, acesulfame K, erythritol, xylitol, sorbitol and tagatose. These are “frequently added to ultra-processed products, including flavored water, soft drinks, energy drinks, yogurt and desserts marketed as low in calories.”

Researchers found that the people who consumed the highest amount of artificial sweeteners “experienced a 62% faster rate of cognitive decline than those with the lowest intake,” said USA Today, a rate “estimated to be comparable to about 1.6 additional years of brain aging.” People who were in the mid-range of consumption “experienced cognitive decline that was 35% faster than those in the lowest-intake group.” The memory loss itself was also most prevalent in study participants who were under 60; researchers “did not find the same association among participants older than 60,” said the study.

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When it came to the amount of sweetener consumed, those in the “lowest consumption group averaged 20 milligrams per day, while those in the highest group averaged 191 milligrams per day,” said the study. Regarding aspartame, one of the most common artificial sweeteners, the “amount consumed by the highest group was roughly equal to the aspartame in one can of diet soda.”

What is the bigger picture?

This study suggests that sugar substitutes are not as good for you as their marketing makes them seem. “Low- and no-calorie sweeteners are often seen as a healthy alternative to sugar; however, our findings suggest certain sweeteners may have negative effects on brain health over time,” the lead study author, Dr. Claudia Kimie Suemoto of Brazil’s University of Sao Paulo, said in a press release.

This is not the only new study to suggest that artificial sweeteners have negative health effects; recent research published in the journal Current Atherosclerosis Reports showed that these chemicals are “linked to higher fasting insulin levels and a higher HbA1c — a measure of long-term blood sugar control,” said HealthDay. It also “found that people who consume more artificial sweeteners may have a higher risk of cardiometabolic conditions, including type 2 diabetes and heart disease.”


When it comes to memory issues, scientists are careful to point out that this research doesn’t necessarily mean artificial sweeteners cause lapses. The study “identified a relationship between sweetener intake and cognitive decline but could not determine whether the sweeteners caused the changes,” said USA Today. The data also “did not include every artificial sweetener currently used in foods and beverages,” and Suemoto emphasized that more research was needed.

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